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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MRPL23
All Species:
27.88
Human Site:
Y56
Identified Species:
51.11
UniProt:
Q16540
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16540
NP_066957.3
153
17781
Y56
T
R
V
D
L
R
N
Y
L
E
G
I
Y
N
V
Chimpanzee
Pan troglodytes
XP_508219
185
20823
Y88
T
R
V
D
L
R
N
Y
L
E
G
I
Y
N
V
Rhesus Macaque
Macaca mulatta
XP_001092196
153
17778
Y56
T
R
V
D
L
R
N
Y
L
E
S
I
Y
N
V
Dog
Lupus familis
XP_540784
195
22748
Y98
T
R
V
D
L
R
N
Y
L
E
R
I
Y
N
V
Cat
Felis silvestris
Mouse
Mus musculus
O35972
146
17103
V51
I
P
M
E
M
T
R
V
D
L
R
N
Y
L
E
Rat
Rattus norvegicus
Q63750
146
17032
V51
I
P
M
E
M
T
R
V
D
L
R
N
Y
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517094
106
11828
K11
K
L
F
A
I
G
F
K
T
V
A
P
S
D
P
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089781
153
18185
Y56
T
K
V
D
V
Q
N
Y
L
Q
R
I
Y
N
A
Zebra Danio
Brachydanio rerio
Q6IQS9
153
18239
Y56
T
K
C
D
V
R
N
Y
L
E
K
I
Y
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W021
150
17859
Y55
T
K
Y
D
V
R
N
Y
L
E
K
I
Y
K
L
Honey Bee
Apis mellifera
XP_001120599
144
17348
R49
H
V
S
M
E
M
T
R
M
D
I
K
N
Y
L
Nematode Worm
Caenorhab. elegans
Q9GYS9
159
19076
Y59
S
R
H
D
I
R
E
Y
L
T
K
I
Y
D
L
Sea Urchin
Strong. purpuratus
XP_792235
148
17360
K53
Q
M
T
K
F
D
V
K
N
Y
L
E
N
V
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81
92.1
64
N.A.
83.6
84.9
N.A.
30.7
N.A.
65.3
61.4
N.A.
40.5
40.5
32.7
49
Protein Similarity:
100
82.1
96
72.3
N.A.
88.2
89.5
N.A.
47
N.A.
82.3
78.4
N.A.
56.2
60.7
53.4
65.3
P-Site Identity:
100
100
93.3
93.3
N.A.
6.6
6.6
N.A.
0
N.A.
60
66.6
N.A.
60
0
46.6
0
P-Site Similarity:
100
100
93.3
93.3
N.A.
26.6
26.6
N.A.
13.3
N.A.
86.6
86.6
N.A.
80
20
73.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
8
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
62
0
8
0
0
16
8
0
0
0
16
0
% D
% Glu:
0
0
0
16
8
0
8
0
0
47
0
8
0
0
16
% E
% Phe:
0
0
8
0
8
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
0
0
16
0
0
0
0
% G
% His:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
16
0
0
0
16
0
0
0
0
0
8
62
0
0
0
% I
% Lys:
8
24
0
8
0
0
0
16
0
0
24
8
0
8
0
% K
% Leu:
0
8
0
0
31
0
0
0
62
16
8
0
0
16
24
% L
% Met:
0
8
16
8
16
8
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
54
0
8
0
0
16
16
39
0
% N
% Pro:
0
16
0
0
0
0
0
0
0
0
0
8
0
0
8
% P
% Gln:
8
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
39
0
0
0
54
16
8
0
0
31
0
0
0
0
% R
% Ser:
8
0
8
0
0
0
0
0
0
0
8
0
8
8
0
% S
% Thr:
54
0
8
0
0
16
8
0
8
8
0
0
0
0
0
% T
% Val:
0
8
39
0
24
0
8
16
0
8
0
0
0
8
39
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
62
0
8
0
0
77
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _